Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota

Abstract The present review aims the discussion of impact bioprospection initiative developed by projects associated to BIOprospecTA, a subprogram program BIOTA, supported FAPESP. This brings summary main results produced investigating natural products (NPs) from non-plants organisms, as examples success this initiative, focusing on progresses achieved related NPs macroalgae, marine invertebrates, arthropods and microorganisms. Macroalgae are one most studied groups in Brazil with isolation many bioactive compounds including lipids, carotenoids, phycocolloids, lectins, mycosporine-like amino acids halogenated compounds. Marine invertebrates microorganisms have been more systematically last thirty years, revealing unique compounds, potent biological activities. venoms Hymenopteran insects were also extensively studied, resulting identification hundreds peptides, which used create chemical library that contributed for leader models development antifungal, antiparasitic, anticancer built knowledge permitted an equine hyperimmune serum anti honeybee venom. Amongst bioprospecting strategy was understand molecular basis intra- interspecies interactions (Chemical Ecology), translating possible biotechnological applications. discussed here reinforce importance BIOprospecTA research highly innovative potential Brazil.